Charles G. ARNOLD,Agis Kydonieus,Thomas M. Rossi,Alfred F. Altomari
申请号:
US16045338
公开号:
US20180325916A1
申请日:
2018.07.25
申请国别(地区):
US
年份:
2018
代理人:
摘要:
A composition for transdermal delivery of a progestin for progestin hormone therapy is disclosed. Also disclosed is a transdermal delivery device comprising the composition. For progestin-only hormone therapy, the composition contains an anti-oxidant and does not contain an estrogen. For therapy involving a progestin and an estrogen, the composition contains the progestin, the estrogen and an additional anti-oxidant. Methods of improving the stability of progestin-containing compositions comprising oxidative agents are also disclosed. The methods comprise including one or more anti-oxidants in the compositions.