Aichi Medical University;National Institutes of Biomedical Innovation, Health and Nutrition
发明人:
申请号：
EP18775819.8
公开号：
EP3604531A1
申请日:
2018.02.20
申请国别(地区):
EP
年份:
2020
代理人:
摘要：
The present invention provides an antisense oligonucleotide for inhibiting biosynthesis of chondroitin sulfate. The antisense oligonucleotide comprises at least one modified nucleotide, wherein the antisense oligonucleotide suppresses expression of one or both of the chondroitin sulfate N-acetylgalactosaminyltransferase-1 (CSGalNAcT1) gene and the chondroitin sulfate N-acetylgalactosaminyltransferase-2 (CSGalNAcT2) gene.
