COMPOSITION FOR CELL SENESCENCE COMPRISING AN INHIBITOR AGAINST HEPARAN SULFATE 2-O SULFOTRANSFERASE 1 GENE, OR A PROTEIN ENCODED BY THE GENE AND METHOD FOR INDUCING CELL SENESCENCE USING THE SAME农业专利-农业专业知识服务系统

发明人:: LEE, JAE SUN,이재선,JUNG, SEUNG HEE,정승희,KIM, BONG CHO,김봉조,LEE, HYUNG CHUL,이형철,LEE, JAE SUNKR,JUNG, SEUNG HEEKR,KIM, BONG CHOKR,LEE, HYUNG CHULKR

摘要：: The present invention relates to a composition for including cell senescence and a method for inducing cell senescence. The composition can induce cell senescence by inhibiting the heparan sulfate 2-O sulfotransferase 1 (HS2ST1) gene in a tumor cell and thus provides an anti-cancer effect in a tumor cell. In the present invention, a composition for inducing cell senescence includes an inhibitor against the HS2ST1 gene or protein encoded by the gene.본 발명은 세포 노화 유도용 조성물 및 이를 이용한 세포 노화 유도 방법에 관한 것으로, 상기 조성물은 종양세포에서 HS2ST1 유전자를 억제하여 세포의 노화를 유도할 수 있으므로, 종양세포에서 항암 효과를 나타낼 수 있다.