The present application discloses a multi-component combination immunopotentiator and its applications. The present invention relates to the production of a multi-component compounding immunopotentiator and application to a swine foot-and-mouth disease vaccine. In the present invention, a swine and foot-and-mouth disease vaccine is used as a subject of research, and based on this, several types of immunopotentiators having a markedly immunopotentiating action are selected and used as a multi-component immunopotentiator. After mixing the agents, vaccine immunized pigs were prepared. From the results of animal experiments, the present invention has a markedly immunopotentiating effect, and after vaccination with a vaccine containing a multi-component immunopotentiator once, the window period of antibody production is shortened to 7 days, and a liquid phase blocking ELISA antibody The titer was significantly higher, the antibody pass rate was significantly increased, the antibody duration could be extended to at least 7 months, and there were no safe and obvious immune side reactions. [Selection figure] None本願は複数成分配合免疫増強剤およびその応用を開示する。本発明は複数成分配合免疫増強剤の製造および豚口蹄疫ワクチンへの応用に関する。本発明は豚口蹄疫ワクチンを研究の主体として、これをもとに、数種類の著しく免疫増強作用を有する免疫増強剤を選択して複数成分配合免疫増強剤に使用して、抗原／ワクチンと免疫増強剤を混合した後、ワクチン免疫豚を作製した。動物実験の結果から、本発明は著しく免疫増強作用を有し、複数成分配合免疫増強剤を含むワクチンを１回接種した後、抗体生成のウィンドウピリオドを７日間に短縮し、液相ブロッキングＥＬＩＳＡ抗体力価が著しく高くなり、抗体の合格率が著しく上昇し、抗体持続期間を少なくとも７ヶ月まで延ばすことができ、かつ安全で、明らかな免疫副反応が認められなかった。【選択図】なし
