Jin CHEN,Xiaoming YU,Qisheng ZHENG,Liting HOU,Yiwei WANG,Yuanpeng ZHANG,Xuwen QIAO,Jibo HOU
申请号:
US16063209
公开号:
US20200261570A1
申请日:
2017.07.28
申请国别(地区):
US
年份:
2020
代理人:
摘要:
A compound immunopotentiator and application thereof relates to the preparation of the compound immunopotentiator and the application thereof in a foot-and-mouth disease vaccine of pigs. The foot-and-mouth disease vaccine of pigs is taken as a research subject, and on this basis, several immunopotentiators having obvious immunopotentiating effects are selected for the compound immunopotentiator, and an antigen/vaccine is mixed with the immunopotentiator to prepare a vaccine-immunized pig. After immunizing the vaccine containing the compound immunopotentiator, a window period for antibody production can be significantly shortened to 7 days; a LPB-ELISA antibody titer is significantly improved, and an antibody pass rate is significantly increased; an immune protection period is also significantly extended, at least up to 7 months; and the compound immunopotentiator is safe, and has no obvious side effects of immunity.