The present invention relates to di-pidotimod benzathine. In particular, it relates to di-pidotimod benzathine in solid form such as in crystalline or amorphous； specific polymorphs are also disclosed such as Form M, Form H and hydrate Form H of di-pidotimod benzathine. In an additional aspect of the invention, solvates and cocrystals of hydrate Form H di-pidotimod benzathine are provided. In further aspects of the invention, processes for making solid di-pidotimod benzathine, crystalline di-pidotimod benzathine, amorphous di-pidotimod benzathine, Form M di-pidotimod benzathine, hydrate Form H di-pidotimod benzathine and Form H di-pidotimod benzathine are provided. In additional aspects of the invention, methods of treating infections or inflammatory diseases using one or more of di-pidotimod benzathine, solid di- pidotimod benzathine, crystalline di-pidotimod benzathine； amorphous di- pidotimod benzathine, Form M di-pidotimod benzathine, Form H di-pidotimod benzathine or solvates, cocrystals or hydrates thereof are provided.La présente invention concerne la di-pidotimod benzathine. En particulier, l'invention concerne la di-pidotimod benzathine sous forme solide cristalline ou amorphe ； l'invention concerne également des polymorphes spécifiques comme la forme M, la forme H et la forme hydrate H de la di-pidotimod benzathine. Dans un autre aspect de l'invention, l'invention concerne des solvates et des co-cristaux de l'hydrate Forme H de la di-pidotimod benzathine. Dans d'autres aspects, l'invention concerne des procédés permettant de fabriquer la di-pidotimod benzathine solide, la di-pidotimod benzathine cristalline, la di-pidotimod benzathine amorphe, la forme M de la di-pidotimod benzathine, la forme hydrate H de la di-pidotimod benzathine et la forme H de la di-pidotimod benzathine. Dans des aspects supplémentaires, l'invention concerne des procédés de traitement d'infections ou de maladies inflammatoires à l'aide d'une ou plusieurs formes parmi la di-pidotimod
