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VIRAL PARTICLE FOR RNA TRANSFER, ESPECIALLY INTO CELLS INVOLVED IN IMMUNE RESPONSE
专利权人:
FLASH THERAPEUTICS
发明人:
BOUILLE, Pascale,DUTHOIT, Christine,LAMOUROUX, Lucille
申请号:
SG11201810014U
公开号:
SG11201810014UA
申请日:
2017.05.12
申请国别(地区):
SG
年份:
2018
代理人:
摘要:
VIRAL PARTICLE FOR RNA TRANSFER, ESPECIALLY INTO CELLS INVOLVED IN IMMUNE RESPONSE The present invention relates to retroviral particle comprising a protein derived from the Gag polyprotein, an envelope protein, optionally an integrase and at least two 5 encapsidated non-viral RNAs, the encapsidated non-viral RNAs each comprising an RNA sequence of interest bound to an encapsidation sequence, each encapsidation sequence being recognized by a binding domain introduced into the protein derived from the Gag polyprotein and/or into the integrase, and at least one of said sequences of interest of the encapsidated non-viral RNAs comprises a part coding at least one epitope 10 and/or at least one molecular structure specifically recognizing an epitope. (No Suitable Figure)
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中国工程科技知识中心
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