Mesenchymal precursor cell

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专利权人:

Inc.;Mesoblast

发明人:

Gronthos, Stan,Simmons, Paul,Zannettino, Andrew

申请号：

AU2011253659

公开号：

AU2011253659B2

申请日:

2011.11.24

申请国别(地区):

AU

年份:

2014

代理人:

摘要：

#$%^&*AU2011253659B220140515.pdf#####ABSTRACT A method of enriching mesenchymal precursor cells including the step of enriching for cells based on at least two markers. The markers may be either i) the presence of markers specific for mesenchymal precursor cells, ii) the absence of markers specific for differentiated mesenchymal cells, or iii) expression levels of markers specific for mesenchymal precursor cells. The method may include a first solid phase sorting step utilising MACS recognising expression of the antigen to the STRO-1 Mab, followed by a second sorting step utilising two colour FACS to screen for the presence of high level STRO-1 antigen expression as well as the expression of VCAM-1.

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中国工程科技知识中心

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