Haydeh Payami,Taye H. Hamza,Stewart A. Factor,John Nutt,Cyrus Zabetian,Honglei Chen,Erin Hill Burns
申请号:
US13574000
公开号:
US20130324503A1
申请日:
2012.10.19
申请国别(地区):
US
年份:
2013
代理人:
摘要:
The present invention relates to methods of treatment for Parkinson Disease (PD) in a person by identifying gene variants which may indicate a more favorable response to specific medicaments, thereby allowing for personalized or individualized treatment. The present invention relates to a method of screening for a genetic predisposition to PD in a person. The present invention is also directed to a method of testing a person for the presence of particular gene variants, wherein the presence of a gene variant indicates a higher predisposition to PD, and the absence of a gene variant indicates a lower predisposition to PD, compared to a control sample. The present invention further relates to methods and kits for treating, or inhibiting the development of, PD in a person. The present invention is also directed to a method of identifying the heritage of an individual based on the genetic profile of the individual.