Toufike Kanouni,Jeffrey Alan Stafford,James Marvin Veal,Michael Brennen Wallace
申请号:
US14134989
公开号:
US08969343B2
申请日:
2013.12.19
申请国别(地区):
US
年份:
2015
代理人:
摘要:
The present invention relates generally to compositions and methods for treating cancer and neoplastic disease. Provided herein are substituted 3-aminopyridine derivative compounds, substituted 3-aminopyridazine derivative compounds, and pharmaceutical compositions comprising said compounds. The subject compounds and compositions are useful for inhibition histone demethylase. Furthermore, the subject compounds and compositions are useful for the treatment of cancer, such as prostate cancer, breast cancer, bladder cancer, lung cancer and/or melanoma and the like.