"method for producing methyl-{4,6-diamino-2-[1-(2-fluorobenzyl)-1h-pyrazolo[3,4-b]pyridino-3-yl]pyrimidino-5-yl} methyl carbamate and its purification for use therof as pharmaceutical substance"

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专利权人:

发明人:

FRANZ JOSEF MAIS,JOACHIM REHSE,WINFRIED JOENTGEN,KONRAD SIEGEL

申请号：

IN4635/DELNP/2012

公开号：

IN2012DN04635A

申请日:

2012.05.25

申请国别(地区):

IN

年份:

2015

代理人:

摘要：

The present invention relates to processes for preparing methyl {4,6-diamino-2-[l-(2-fluorobenzyl)-lH-pyrazolo[3,4-b]pyridin-3-yl]pyrimidin-5-yl}carbamate, i.e. the compound of the formula (I) and to a process for purifying the crude product of the formula (I) for use as pharmaceutically active compound, where, for purification, methyl {4,6-diamino-2-[l-(2-fluorobenzyl)-lH-pyrazolo[3,4-b]pyridin-3-yl]pyrimidin-5-yl}carbamate sulphinyldimethane (1:2) of the formula (II) is isolated as intermediate or is generated as intermediate in this purification process, if appropriate present in a mixture.

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