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SOLID PHARMACEUTICAL COMPOSITION FOR ORAL ADMINISTRATION
专利权人:
发明人:
申请号:
EP10840973.1
公开号:
EP2520299A1
申请日:
2010.12.27
申请国别(地区):
EP
年份:
2012
代理人:
摘要:
The present invention relates to a solid pharmaceutical composition for oral administration, containing the following components (A) and (B): (A)2-[4-[2-(benzimidazol-2-ylthio)ethyl]piperazin-1-yl]-N-[2,4 -bis(methylthio)-6-methyl-3-pyridyl]acetamide (compound a) or an acid addition salt thereof, and (B) organic acid selected from the group consisting of tartaric acid, malic acid, ascorbic acid and benzoic acid. An improvement is achieved in the dissolubility of the compound a, which is useful as a therapeutic agent for hypercholesterolemia, arteriosclerosis, and the like.
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