Pku Healthcare Industry Group Co., Ltd.;Pkucare Pharmaceutical R&D Center;Peking University Founder Group Co., Ltd
发明人:
申请号:
EP14888830.8
公开号:
EP3130588A1
申请日:
2014.12.30
申请国别(地区):
EP
年份:
2017
代理人:
摘要:
The present invention provides a polysubstituted pyridine compound of Formula I, a preparation method, a use and a pharmaceutical composition thereof. The polysubstituted pyridine compound of Formula I according to the present invention has an excellent anti-tumor effect, can inhibit various cell kinases simultaneously, has significantly excellent pharmacokinetic characteristics, and is very suitable for oral and intravenous administration. The pharmaceutical composition according to the present invention can be useful for treating tumors and cancers.