PEKING UNIVERSITY FOUNDER GROUP CO., LTD.;PKUCARE PHARMACEUTICAL R&D CENTER;PKU HEALTHCARE INDUSTRY GROUP CO., LTD.
发明人:
Chongqin Yi,Heng Xu,Jing Tao,Songwen Lin,Fangbin Han
申请号：
US15302723
公开号：
US09902709B2
申请日:
2014.12.30
申请国别(地区):
US
年份:
2018
代理人:
摘要：
The present invention provides a polysubstituted pyridine compound of Formula I, a preparation method, a use and a pharmaceutical composition thereof. The polysubstituted pyridine compound of Formula I according to the present invention has an excellent anti-tumor effect, can inhibit various cell kinases simultaneously, has significantly excellent pharmacokinetic characteristics, and is very suitable for oral and intravenous administration. The pharmaceutical composition according to the present invention can be useful for treating tumors and cancers.
