This invention provides an optical biosensor module, which comprises a circuit board, a light-receiving unit stacked on the circuit, and a light-emitting unit stacked on the light-receiving unit. The light-receiving unit and the light-emitting unit have a light-blocking structure respectively which can avoid a light of generating from the light-emitting unit irradiating to the light-receiving unit directly. This invention also provides a method for making the optical biosensor module stated above.一種光學式生醫感測器模組，包含一電路板、一疊置於電路板的收光單元以及疊置於該收光單元的一發光單元。其中發光單元與收光單元間具有對應的擋光結構，以避免發光單元所發出的光直接射至收光單元。本發明還提供一種前述光學式生醫感測器模組的製作方法。
