CHAO, ROBERT S.,RAPTA, MIROSLAV,COLSON, PIERRE-JEAN
申请号:
CA2575874
公开号:
CA2575874C
申请日:
2005.08.15
申请国别(地区):
CA
年份:
2012
代理人:
摘要:
The invention provides a crystalline 1,2-ethanedisulfonic acid salt ofbiphenyl-2-ylcarbamic acid 1-[2-(2-chloro-4-{[(R)-2-hydroxy-2-(8-hydroxy-2-oxo-1,2-dihydroquinolin-5-yl)ethylamino]methyl}-5-methoxyphenylcarbamoyl)ethyl]piperidin-4-yl ester or a solvate thereof. Thisinvention also provides pharmaceutical compositions comprising such a salt orprepared using such a salt; processes and intermediates for preparing such asalt; and methods of using such a salt to treat a pulmonary disorder.