CHAO, ROBERT S.,RAPTA, MIROSLAV,COLSON, PIERRE-JEAN
申请号:
DK05803280
公开号:
DK1778672T3
申请日:
2005.08.15
申请国别(地区):
DK
年份:
2013
代理人:
摘要:
The invention provides a crystalline 1,2-ethanedisulfonic acid salt of biphenyl-2-ylcarbamic acid 1-[2-(2-chloro-4-{[(R)-2-hydroxy-2-(8-hydroxy-2-oxo-1,2-dihydroquinolin-5-yl)ethylamino]methyl}-5-methoxyphenylcarbamoyl)ethyl]piperidin-4-yl ester or a solvate thereof. This invention also provides pharmaceutical compositions comprising such a salt or prepared using such a salt; processes and intermediates for preparing such a salt; and methods of using such a salt to treat a pulmonary disorder.