Anhydrous polymorphs of (2r,3s,4r,5r)-5-(6-(cyclopentylamino)-9h-purin-9-yl)-3,4-dihydroxytetrahydrofuran-2-yl)} methyl nitrate and processes of preparation thereof

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专利权人:

INOTEK PHARMACEUTICALS CORPORATION

发明人:

Mcvicar William K.

申请号：

NZ62777813

公开号：

NZ627778A

申请日:

2013.01.25

申请国别(地区):

NZ

年份:

2017

代理人:

摘要：

Disclosed are anhydrous polymorph forms of (2R,3S,4R,5R)-5-(6-(cyclopentylamino)-9H-purin-9-yl)-3,4-dihydroxytetrahydrofuran-2-yl) methyl nitrate (Compound A). The compounds are selective adenosine A1 receptor agonists for use in the treatment of elevated intra-ocular pressure.

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