BOUCHARD, HERVE,赫夫 柏查德,赫夫 柏查德,CHARI, RAVI V. J.,瑞维V J 查立,瑞維V J 查立,COMMERCON, ALAIN,艾伦 科摩康,艾倫 科摩康,DENG, YONGHONG,邓永宏,鄧永宏,GAUZY, LAURENCE,劳伦斯 高兹,勞倫斯 高茲
申请号：
TW097127553
公开号：
TWI500618B
申请日:
2008.07.18
申请国别(地区):
TW
年份:
2015
代理人:
摘要：
The invention relates to novel tomaymicine derivatives comprising a linker. It also relates to the conjugate molecules that comprise one or more of said tomaymicine derivatives covalently linked to a cell binding agent through a linking group that is present on the linker of the tomaymycin derivative. It also relates to the preparation of the tomaymicine derivatives and of the conjugate molecules.本發明係關於包含連接子之新穎茅屋黴素衍生物。本發明亦係關於結合物分子,其包含一或多個與細胞結合劑經由茅屋黴素衍生物之連接子上所存在之鍵聯基團共價鍵聯之該等茅屋黴素衍生物。本發明亦係關於茅屋黴素衍生物及結合物分子之製備。(無元件符號說明)
