Hervé Bouchard,Ravi V. J. Chari,Alain Commerçon,Yonghong Deng,Laurence Gauzy
申请号:
US12689797
公开号:
US08404678B2
申请日:
2010.01.19
申请国别(地区):
US
年份:
2013
代理人:
摘要:
The invention relates to novel tomaymicine derivatives comprising a linker. It also relates to the conjugate molecules that comprise one or more of said tomaymicine derivatives covalently linked to a cell binding agent through a linking group that is present on the linker of the tomaymycin derivative. It also relates to the preparation of the tomaymicine derivatives and of the conjugate molecules.