Carl H. June,Bruce L. Levine,David L. Porter,Michael D. Kalos,Michael C. Milone
申请号:
US14568195
公开号:
US20150118202A1
申请日:
2014.12.12
申请国别(地区):
US
年份:
2015
代理人:
摘要:
The present invention provides compositions and methods for treating cancer in a human. The invention includes relates to administering a genetically modified T cell to express a CAR wherein the CAR comprises an antigen binding domain, a transmembrane domain, a costimulatory signaling region, and a CD3 zeta signaling domain