Broth microdilution method for evaluating and determining minimal inhibitory concentration of antibacterial polypeptides

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专利权人:

ContraFect Corporation

发明人:

Schuch, Raymond

申请号：

AU2017263563

公开号：

AU2017263563A1

申请日:

2017.05.12

申请国别(地区):

AU

年份:

2018

代理人:

摘要：

The present invention provides components, assays and methods for evaluating antibacterial effectiveness and determining minimal inhibitory concentration (MIC) of polypeptides, including lysin polypeptides, that kill bacteria. Modified broth microdilution components and methods are provided, including supplements to enable accurate MIC determination mimicking lysin polypeptide activity in human matrices including serum and blood.

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