John David Lawson,Toufike Kanouni,Michael B. Wallace,Qing Dong
申请号:
US13787514
公开号:
US20130184252A1
申请日:
2013.03.06
申请国别(地区):
US
年份:
2013
代理人:
摘要:
Disclosed are JAK inhibitors of formula Iwhere G1, R1, R2, R3, R4, R5, R6, and R7 are defined in the specification. Also disclosed are pharmaceutical compositions, kits and articles of manufacture which contain the compounds, methods and materials for making the compounds, and methods of using the compounds to treat diseases, disorders, and conditions involving the immune system and inflammation, including rheumatoid arthritis, hematological malignancies, epithelial cancers (i.e., carcinomas), and other diseases, disorders or conditions associated with JAK.