DONG, QING,LAWSON, JOHN DAVID,WALLACE, MICHAEL B.,KANOUNI, TOUFIKE
申请号:
PL10725338
公开号:
PL2440558T3
申请日:
2010.06.08
申请国别(地区):
PL
年份:
2015
代理人:
摘要:
Disclosed are JAK inhibitors of formula I where G1, R1, R2, R3, R4, R5, R6, and R7 are defined in the specification. Also disclosed are pharmaceutical compositions, kits and articles of manufacture which contain the compounds, methods and materials for making the compounds, and methods of using the compounds to treat diseases, disorders, and conditions involving the immune system and inflammation, including rheumatoid arthritis, hematological malignancies, epithelial cancers (i.e., carcinomas), and other diseases, disorders or conditions associated with JAK.