PROBLEM TO BE SOLVED: To provide a method for manufacturing a hollow fiber membrane, which can bring about the hollow fiber membrane for blood processing, capable of reducing erroneous leak determination and fixing of the hollow fiber membranes to each other while maintaining a high membrane performance.SOLUTION: The method for manufacturing the hollow fiber membrane for the blood processing, wherein the hollow fiber membrane contains a polysulfone-based resin and a hydrophilic polymer, includes the step of using a spinning solution containing the polysulfone-based resin and the hydrophilic polymer with a molecular weight of 300,000 or more and an internal coagulation liquid containing 0.1-10 mass% of the hydrophilic polymer with a molecular weight of 300,000 or more, of simultaneously making the internal coagulation liquid flow out from an inside channel of a double annular nozzle and making the spinning solution flow out from an outside channel of the double annular nozzle, and of congealing them in an external coagulation liquid.COPYRIGHT: (C)2012,JPO&INPIT【課題】 高い膜性能を維持しつつ、リーク誤判定及び中空糸膜同士の固着を低減できる血液処理用の中空糸膜を得ることができる中空糸膜の製造方法を提供すること。【解決手段】 血液処理用の中空糸膜の製造方法であって、中空糸膜は、ポリスルホン系樹脂と親水性高分子とを含むものであり、ポリスルホン系樹脂及び分子量300,000以上の親水性高分子を含む紡糸原液と、分子量300,000以上の親水性高分子を0.1~10質量%含む内部凝固液とを用い、2重環状ノズルの内側流路から内部凝固液を、2重環状ノズルの外側流路から紡糸原液を、それぞれ同時に流出させ、外部凝固液中で凝固させる工程を有することを特徴とする方法。【選択図】 図2
