A nebulizer apparatus according to the present invention has an enclosure including a primary chamber of ambient air, a medicant chamber and a secondary chamber. The secondary chamber is for containing water and includes an ultrasonic transducer and is in communication with the primary chamber. The apparatus further has a first switch for activating pump means for evacuating air from the primary chamber after which the transducer is activated for a predetermined time. The pump stops after a predetermined pressure is achieved. The apparatus has a valve that opens allowing a dose of powdered medicine in the medicant chamber to move into the vapor-rich primary chamber to seed and form a cloud laden with medicine. A mouthpiece is attached to said primary chamber to allow the patient to suck and inhale the cloud. The mouthpiece may further include a one way valve that seals the mouthpiece during evacuation and upon the patient sucking the tubing of the mouthpiece the valve opens to allow the cloud to be inhaled.