PROBLEM TO BE SOLVED: To find a novel material which can efficiently proliferate stem cells while keeping them in an undifferentiated state and provide such a material as an agent for maintaining the undifferentiated state of stem cells or an agent for promoting the proliferation thereof.SOLUTION: The present invention provides an agent for maintaining the undifferentiated state of stem cells or an agent for promoting the proliferation thereof, comprising Atractylodes japonica extract as an active ingredient.SELECTED DRAWING: NoneCOPYRIGHT: (C)2017,JPO&INPIT【課題】幹細胞を、未分化状態を維持させたまま、効率良く増殖させることができる新たな物質を見出し、幹細胞の未分化状態維持剤又は増殖促進剤として提供すること。【解決手段】オケラの抽出物を有効成分として含有する、幹細胞の未分化状態維持剤又は増殖促進剤。【選択図】なし