PROBLEM TO BE SOLVED: To discover a new material that can efficiently proliferate stem cells while maintaining their undifferentiated state to be provided as an agent for maintaining the undifferentiated states of stem cells or an agent for promoting the proliferation of stem cells.SOLUTION: The present invention provides an agent for maintaining the undifferentiated states of stem cells or an agent for promoting the proliferation of stem cells, the agent containing one or more crude drug extract selected from Wolfiporia extensa, Alisma orientale Juzepczuk, and Cnidium rhizome as an active ingredient.SELECTED DRAWING: NoneCOPYRIGHT: (C)2018,JPO&INPIT【課題】幹細胞を、未分化状態を維持させたまま、効率良く増殖させることができる新たな物質を見出し、幹細胞の未分化状態維持剤又は増殖促進剤として提供すること。【解決手段】マツホド、サジオモダカ及びセンキュウから選択される1種又は2種以上の生薬の抽出物を有効成分として含有する、幹細胞の未分化状態維持剤又は増殖促進剤。【選択図】なし