The Broad Institute, Inc.;Dana-Farber Cancer Institute, Inc.;The General Hospital Corporation
发明人:
WAGNER, Florence Fevrier,PAN, Jennifer Q.,DANDAPANI, Sivaraman,GERMAIN, Andrew,HOLSON, Edward,MUNOZ, Benito,NAG, Partha P.,WEIWER, Michel,LEWIS, Michael C.,HAGGARTY, Stephen J.,BISHOP, Joshua A.,STEGM
申请号：
ES13780300
公开号：
ES2719776T3
申请日:
2013.10.11
申请国别(地区):
ES
年份:
2019
代理人:
摘要：
The present invention provides compounds of formula I, pharmaceutically acceptable salts thereof, and pharmaceutical compositions thereof. Compounds of the present invention are useful for inhibiting kinase (e.g., GSK3 (e.g., GSK3&alpha； or GSK3&bgr；) or CK1) activity. The present invention further provides methods of using the compounds described herein for treating kinase-mediated disorders, such as neurological diseases, psychiatric disorders, metabolic disorders, and cancer.
