The Broad Institute, Inc.;The General Hospital Corporation;Dana-Farber Cancer Institute, Inc.
发明人:
WAGNER Florence Fevrier,PAN Jennifer Q.,DANDAPANI Sivaraman,GERMAIN Andrew,HOLSON Edward,MUNOZ Benito,NAG Partha P.,WEIWER Michel,LEWIS Michael C.,HAGGARTY Stephen J.,BISHOP Joshua A.,STEGMAIER Kimber
申请号：
SI201331368
公开号：
SI2909204T1
申请日:
2013.10.11
申请国别(地区):
SI
年份:
2019
代理人:
摘要：
The present invention provides compounds of formula I, pharmaceutically acceptable salts thereof, and pharmaceutical compositions thereof. Compounds of the present invention are useful for inhibiting kinase (e.g., GSK3 (e.g., GSK3&alpha； or GSK3&bgr；) or CK1) activity. The present invention further provides methods of using the compounds described herein for treating kinase-mediated disorders, such as neurological diseases, psychiatric disorders, metabolic disorders, and cancer.
