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METHOD FOR PRODUCING RETINAL TISSUE AND RETINA-RELATED CELLS
专利权人:
SUMITOMO CHEMICAL COMPANY, LIMITED;RIKEN
发明人:
Tokushige NAKANO,Yoshiki SASAI,Chikafumi OZONE
申请号:
US16692484
公开号:
US20200102535A1
申请日:
2019.11.22
申请国别(地区):
US
年份:
2020
代理人:
摘要:
The present invention provides a method for producing a retinal progenitor cell, including (1) a first step of subjecting pluripotent stem cells to floating culture in a serum-free medium to form an aggregate of pluripotent stem cells, and (2) a second step of subjecting the aggregate formed in step (1) to floating culture in a serum-free medium or serum-containing medium each being free of a substance acting on the Sonic hedgehog signal transduction pathway but containing a substance acting on the BMP signal transduction pathway, thereby obtaining an aggregate containing retinal progenitor cells.
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