The purpose of the present invention is to provide a combine harvester that can adjust threshing to an optimal state in order to make a loss amount calculated by a threshing drum loss sensor and a shaking loss sensor fall within a loss amount target range, and that can perform feedback control on the basis of the loss amount calculated by the threshing drum loss sensor and the shaking loss sensor and adjust the loss amount so as to fall within the loss amount target range by controlling a dust sending valve, a chaff sieve and vehicle speed. Provided is a combine harvester that is characterized as follows: a loss sensor is disposed at the end of a processing path of reaped grain culm; the dust sending valve and the chaff sieve are connected to a control device; when the dust sending valve, the chaff sieve and a traveling section are subjected to feedback control in order to make a loss value calculated by the loss sensor fall within a loss amount target range, control is performed so as to first adjust the dust sending valve in the case where the loss amount exceeds the target range, adjust the chaff sieve upon reaching a dust sending valve limit value at which the measured loss amount cannot fall within the target range, and then adjust the vehicle speed upon reaching a chaff sieve limit value at which the measured loss amount cannot fall within the target range; and control is performed so as to adjust the vehicle speed when the loss amount falls below the target range, adjust the chaff sieve upon reaching a vehicle speed limit value at which the measured loss amount cannot fall within the target range, and then adjust the dust sending valve upon reaching a chaff sieve limit value at which the measured loss amount cannot fall within the target range.L'objectif de la présente invention est de fournir une moissonneuse-batteuse qui peut ajuster le battage dans un état optimal afin d'amener une quantité de perte calculée par un capteur de perte de tambour de battage et