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神経栄養因子-4(Neurotrophin-4)アンタゴニスト
专利权人:
ライオン株式会社
发明人:
栗田 啓,内山 千代子,吉野 輝彦
申请号:
JP2005332868
公开号:
JP4861686B2
申请日:
2005.11.17
申请国别(地区):
JP
年份:
2012
代理人:
摘要:

PROBLEM TO BE SOLVED: To provide a means for specifying an ingredient which participates in a mechanism causing alopecia in a living body and has an action for especially inhibiting an advance of apoptosis in hair, and for improving mammalian alopecia including male type alopecia.

SOLUTION: The present invention provides an NT-4 activity-inhibiting peptide having a receptor bonding inhibition effect and NT-4 homo/hetero dimer formation inhibition effect necessary for expressing a neurotrophin-4 (NT-4) signal inhibition effect, or a modified product thereof, and provides a use of the peptide or the modified product thereof as a hair-restoring and growing agent.

COPYRIGHT: (C)2007,JPO&INPIT

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