CHRISTOPHER G. WITOWSKI;DENNIS E. KYLE;BRIAN VESELY;BILL J. BAKER;JOHN ALAN MASCHEK
发明人:
BILL J. BAKER,CHRISTOPHER G. WITOWSKI,JOHN ALAN MASCHEK,BRIAN VESELY,DENNIS E. KYLE
申请号:
US14811341
公开号:
US20160030388A1
申请日:
2015.07.28
申请国别(地区):
US
年份:
2016
代理人:
摘要:
In a screening program, the Antarctic sponge Dendrilla membranosa was found to produce diterpenoid secondary metabolites with activity against the leishmaniasis-causing parasite Leishmania donovani. The present invention concerns compositions useful for control of Leishmania spp. parasites in vitro and in vivo and treatment of leishmaniasis; methods for treatment of leishmaniasis; and methods for controlling Leishmania spp. parasites in vitro and in vivo.