TAMPER RESISTANT DOSAGE FORM WITH BIMODAL RELEASE PROFILE MANUFACTURED BY CO-EXTRUSION

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专利权人:

GRUNENTHAL GMBH

发明人:

GEISSLER, ANJA,DENKER, JANA,WENING, KLAUS,BARNSCHEID, LUTZ

申请号：

CA2933983

公开号：

CA2933983A1

申请日:

2014.12.15

申请国别(地区):

CA

年份:

2015

代理人:

摘要：

11GRA3639-WO/JBdk Summary: The invention relates toa monolithic pharmaceutical dosage form comprising a hot melt-extruded first segment (S ) and a second segment (S 2 ) whereinthe first segment (S ) contains at least a first pharmacologically active ingredient (A ) and/or the second segment (S 2 )contains at least a second pharmacologically active ingredient (A 2 ) andthe segment (S ) and/or the segment (S 2 ) is tamper-resistantand/orexhibits a breaking strength of at least 300N.

来源网站：

中国工程科技知识中心

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http://www.ckcest.cn/home/