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IMIDAZO[4,5-D]PYRIMIDINES, THEIR USES AND METHODS OF PREPARATION
专利权人:
发明人:
김 청 유.,네이츠 조한,오아레 데이비드 에이.,퓌르스틴거 게르하르트
申请号:
KR1020077004804
公开号:
KR1012384300000B1
申请日:
2005.07.26
申请国别(地区):
KR
年份:
2013
代理人:
摘要:
The present invention relates to pharmaceutical compositions for the treatment or prevention of viral infections comprising as an active principle at least one compound having the general formula (A): wherein U is N or C; X is selected from C1-C10 alkylene, C2-10 alkenylene or C2-10 alkynylene, where each may include one or more intrachain heteroatoms selected from O, S, or NR11, provided any such heteroatom is not adjacent to the N in the ring; R3 is selected from aryl, aryloxy, arylthio, cycloalkyl, cycloalkenyl, cycloalkynyl, aryl-N(R10)—, or heterocycle, where each said substituent is optionally substituted with at least one R17, provided that for cycloalkenyl the double bond is not adjacent to a nitrogen; and the other substituents are described in the specification. The invention also relates to processes for the preparation of compounds according to the invention having above mentioned general formula, their pharmaceutically acceptable formulations and their use as a medicine or to treat or prevent viral infections.본 발명은 활성원으로서 적어도 하나의 일반식 (A)을 갖는 이미다조[4,5-d]피리미딘을 포함하는 바이러스 감염의 치료 또는 예방을 위한 약학 조성물에 대한 것이다:(A)여기에서, 치환기는 명세서에 기재되어 있다.본 발명은 또한 상기 언급된 일반식을 갖는 본 발명에 따란 화합물의 제조 과정, 그들의 약학적으로 허용가능한 제제 및 의약으로서 또는 바이러스 감염의 치료 또는 예방하는 그들의 용도에 대한 것이다.
来源网站:
中国工程科技知识中心
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