CHUNG-ANG UNIVERSITY INDUSTRY-ACADEMY COOPERATION FOUNDATION
发明人:
LEE, MIN WON,이민원,KIM, MANH HEUN,김많흔
申请号：
KR1020110052741
公开号：
KR1020120135448A
申请日:
2011.06.01
申请国别(地区):
KR
年份:
2012
代理人:
摘要：
PURPOSE: A novel hemiterpene glucoside compound isolated from Ilex Rotunda leaf extract with an antioxidation activity is provided to remove free radicals, to enhance antioxidation activity, and to be used in a cosmetic composition or functional food composition.CONSTITUTION: A hemiterpene glucoside compound is denoted by chemical formula 1 or 2. The compound is isolated from Ilex Rotunda leaves. The compounds are prepared by purifying Ilex Rotunda leaf extract by column chromatography. The Ilex Rotunda leaf extract is prepared using water, anhydrous or hydrous low carbon number alcohols, acetone, ethyl acetate, butyl acetate, or 1,3-butylene glycol. A composition for antioxidation contains the compounds of chemical formula 1 or 2 as an active ingredient. The composition is a cosmetic composition for antioxidation. The cosmetic composition is manufactured in the form of a skin softener, lotion, nutrition cream, massage cream, essence, eye cream, cleansing cream, cleansing form, pack, spray, or powder.COPYRIGHT KIPO 2013본 발명은 항산화 활성을 갖는 먼나무 잎 추출물로부터 분리된 신규한 헤미테르펜 글루코시드 화합물에 관한 것이다. 본 발명의 화합물은 DPPH를 이용한 자유라디칼 소거능 실험에서 아스코르브산과 유사한 정도의 자유라디칼 소거능을 보였으며, 크산틴 산화효소 수퍼옥사이드 소거(Xanthine Oxidase Superoxide Scavenging)활성 평가에서도 우수한 항산화 활성을 나타내었다. 따라서, 본 발명의 화합물은 항산화 용도의 화장품 조성물 또는 기능성 식품 조성물의 활성성분으로 활용될 수 있다.
