Kerschbaumer, Randolf J.,Voelkel, Dirk,Antoine, Gerhard,Scheiflinger, Fritz,Mudde, C. Geert
申请号:
AU2012327159
公开号:
AU2012327159A1
申请日:
2012.10.04
申请国别(地区):
AU
年份:
2013
代理人:
摘要:
The present invention is concerned with the specific and highly sensitive detection of specific CHO-MIF (macrophage migration inhibitory factor from Chinese Ovarian Hamster cell line) complexes in the production of anti-MIF antibodies. The present invention is further concerned with the provision of specific antibodies which can be used for a CHO-MIF detection method. The present invention is also concerned with a CHO MIF knockout cell line and use thereof. The present invention also provides preparations obtained from recombinant production in CHO cell lines which are essentially free of CHO-MIF.