LI, JUN,SAFINA, BRIAN,SUTHERLIN, DANIEL P.,SWEENEY, ZACHARY
申请号:
CA2802808
公开号:
CA2802808A1
申请日:
2011.07.13
申请国别(地区):
CA
年份:
2012
代理人:
摘要:
The invention provides compounds having the general formula (I): and stereoisomers, tautomers, or pharmaceutically acceptable salts thereof, wherein R1, R2, R3, R4 and n are defined herein, compositions including the compounds and method of using the compounds to treat a disease or disorder mediated by the p110 delta isoform of ?I3 kinase selected from immune disorders, cancer, cardiovascular disease, viral infection, inflammation, metabolism/endocrine function disorders and neurological disorders.