Jun Li;Daniel P. Sutherlin;Zachary Sweeney;Brian Safina
发明人:
Jun Li,Brian Safina,Daniel P. Sutherlin,Zachary Sweeney
申请号:
US13181647
公开号:
US08293736B2
申请日:
2011.07.13
申请国别(地区):
US
年份:
2012
代理人:
摘要:
The invention provides compounds having the general formula:and stereoisomers, tautomers, or pharmaceutically acceptable salts thereof, wherein R1, R2, R3, R4 and n are defined herein, compositions including the compounds and method of using the compounds to treat a disease or disorder mediated by the p110 delta isoform of PI3 kinase selected from immune disorders, cancer, cardiovascular disease, viral infection, inflammation, metabolism/endocrine function disorders and neurological disorders.