UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC.;SHARKLET TECHNOLOGIES; INC.;SHARKLET TECHNOLOGIES, INC.
发明人:
MAGIN, CHELSEA MARIE,BRENNAN, ANTHONY B.,WILLENBERG, BRADLEY JAY,SCHULTZ, GREGORY SCOTT,NEALE, DYLAN BURTON
申请号:
CA2983292
公开号:
CA2983292A1
申请日:
2016.04.25
申请国别(地区):
CA
年份:
2017
代理人:
摘要:
Disclosed herein is a multilayered wound dressing comprising a first layer; the first layer including channels that facilitate neovascularization of a wound; and a second layer in contact with the first layer, the second layer having the same or different chemical composition as the first layer; where the second layer comprises at least one surface that has a texture and the direction of the texture is operative to facilitate cell orientation and growth. A method includes forming a first layer of a polymeric material; forming a second layer of the same polymeric material as the first layer on the first layer; and forming a textured surface of the second layer of the same polymeric material as the first layer, the textured surface being operative to facilitate directional cell growth when used in a wound dressing, where the first layer and the second layer are formed using an additive manufacturing process.