UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC.;SHARKLET TECHNOLOGIES, LLC
发明人:
Chelsea Marie MAGIN,Anthony B. BRENNAN,Bradley Jay WILLENBERG,Gregory Scott SCHULTZ,Dylan Burton NEALE
申请号:
US15568767
公开号:
US20180078423A1
申请日:
2016.04.25
申请国别(地区):
US
年份:
2018
代理人:
摘要:
Disclosed herein is a multilayered wound dressing comprising a first layer; the first layer including channels that facilitate neovascularization of a wound; and a second layer in contact with the first layer, the second layer having the same or different chemical composition as the first layer; where the second layer comprises at least one surface that has a texture and the direction of the texture is operative to facilitate cell orientation and growth. A method includes forming a first layer of a polymeric material; forming a second layer of the same polymeric material as the first layer on the first layer; and forming a textured surface of the second layer of the same polymeric material as the first layer, the textured surface being operative to facilitate directional cell growth when used in a wound dressing, where the first layer and the second layer are formed using an additive manufacturing process.