There is provided herein a kind of skin regeneration compositions, and it includes at least one oxidant, at least one light activating agent that can activate the oxidant and at least one healing factors and pharmaceutically acceptable carrier selected from hyaluronic acid, aminoglucose and allantoin.本文提供了一種皮膚再生組合物,其包含至少一種氧化劑、至少一種能够活化所述氧化劑的光活化劑,及至少一種選自透明質酸、葡糖胺和尿囊素的愈合因子,以及藥學上可接受的載體。