P. Martin Petkovich;Joel Z. Melnick;Charles W. Bishop;Eric J. Messner;Samir P. Tabash;Jay A. White
发明人:
Eric J. Messner,P. Martin Petkovich,Jay A. White,Samir P. Tabash,Joel Z. Melnick,Charles W. Bishop
申请号：
US13638845
公开号：
US20130137663A1
申请日:
2011.03.29
申请国别(地区):
US
年份:
2013
代理人:
摘要：
Methods and compositions for reducing serum parathyroid levels in, for example, chronic kidney disease patients are disclosed. In these methods, an effective amount of a modified release formulation of 25-hydroxy vitamin D is orally administered to a patient suffering from secondary hyperparathyroidism to lower the patient's serum intact parathyroid hormone (iPTH) level, while avoiding a surge in serum total 25-hydroxy vitamin D.
