OPKO IRELAND GLOBAL HOLDINGS, LTD.;OPKO RENAL, LLC
发明人:
申请号:
PT11763340
公开号:
PT2552484T
申请日:
2011.03.29
申请国别(地区):
PT
年份:
2020
代理人:
摘要:
Methods and compositions for reducing serum parathyroid levels in, for example, chronic kidney disease patients are disclosed. In these methods, an effective amount of a modified release formulation of 25-hydroxyvitamin D is orally administered to a patient suffering from secondary hyperparathyroidism to lower the patient's serum intact parathyroid hormone (iPTH) level, while avoiding a surge in serum total 25-hydroxyvitamin D.