A safety self-destruction syringe with puncture proof protective sleeve consists of a needlepoint protective sleeve (1), a needlepoint (2), a needle base (3), a puncture proof protective sleeve (4), an adapter member (5), a locking bayonet (6), a liquid pushing cylinder sleeve (7), a core rod (8), and a sealing plug (9). The adapter member (5) is arranged on the top end of the puncture proof protective sleeve (4). The locking baonet (6) is arranged on the puncture proof protective sleeve (4) by bonding or welding. The thread of the Luer connector (10) at the top end of the liquid pushing cylinder sleeve (7) is tightly matched with or engaged with lugs (16) of the adapter member (5). The locking bayonet (6) has elastic hook pieces (18) for locking the adapter member (5).
