COMPOSE D'ACIDE CARBOXYLIQUE A SUBSTITUTION QUINOLINYLE OU SEL PHARMACEUTIQUEMENT ACCEPTABLE DE CELUI-CI, COMPOSITION PHARMACEUTIQUE ET UTILISATION ASSOCIEES

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专利权人:

LTD.;BEIJING KONRUNS PHARMACEUTICAL CO.

发明人:

ZHANG, ZHIQIANG,WANG, XIJUAN,ZHANG, XUEHUI,QIU, JUNXIA,YANG, JIEHE,ZHANG, XIAOKAI,YAO, PENG

申请号：

CA3040788

公开号：

CA3040788A1

申请日:

2017.09.29

申请国别(地区):

CA

年份:

2018

代理人:

摘要：

Provided in the present invention is a quinolinyl-substituted carboxylic acid compound as shown in formula (I) or a pharmaceutically acceptable salt thereof, and also disclosed are a preparation method and the use of the compound and a preparation comprising the quinolinyl-substituted carboxylic acid compound or a pharmaceutically acceptable salt thereof. The compound is an inhibitor of the protein kinase AXL and/or VEGFR2 and can be used for treating diseases caused by aberrant activity of both kinases, such as tumours, etc.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/