Robert A. MacLeod;Brett P. Monia;Jeffrey R. Crosby;Susan M. Freier
发明人:
Brett P. Monia,Jeffrey R. Crosby,Robert A. MacLeod,Susan M. Freier
申请号:
US13262904
公开号:
US20120083522A1
申请日:
2010.04.15
申请国别(地区):
US
年份:
2012
代理人:
摘要:
Disclosed herein are antisense compounds and methods for modulating Factor XI and modulating an inflammatory disease, disorder or condition in an individual in need thereof. Inflammatory diseases in an individual such as arthritis and colitis can be ameliorated or prevented with the administration of antisense compounds targeted to Factor XI.