Generation, characterization and uses thereof of anti-HER3 antibodies

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专利权人:

Merck Sharp & Dohme Corp.

发明人:

Zhang, Ningyan,Presta, Leonard G.

申请号：

AU2011307251

公开号：

AU2011307251A1

申请日:

2011.09.27

申请国别(地区):

AU

年份:

2013

代理人:

摘要：

The present invention relates to humanized Her3 specific antibodies and antigen-binding portions thereof. Nucleic acid molecules encoding the Her3 antibodies as well as methods of use thereof are also disclosed. Also included are pharmaceutical compositions comprising these antibodies and methods of using the antibodies and compositions thereof for treatment and diagnosis of pathological hyperproliferative oncogenic disorders associated with aberrant expression of Her3 or Her2 including aberrant activation of each of these receptors.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/