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COMPOSIÇÕES AQUOSAS ESTABILIZADAS DE AGENTES BLOQUEADORES NEUROMUSCULARES
专利权人:
B. BRAUN MELSUNGEN AG
发明人:
JUAN GIL BÉJAR,CRISTINA TIMONEDA RAMIA
申请号:
PT13766501
公开号:
PT2900216T
申请日:
2013.09.19
申请国别(地区):
PT
年份:
2017
代理人:
摘要:
The invention relates to an aqueous composition comprising a quaternary ammonium blocking agent and a polyhydroxy acid based excipient, and a method for producing said composition. In particular the neuromuscular blocking agent may be a Rocuronium salt and the excipient is an aldonic acid, e. g. gluconic acid or an intramolecular lactone thereof. Furthermore, the invention relates to a liquid pharmaceutical composition comprising said aqueous composition. The compositions of the present invention can further be comprised in a container made of glass or an organic polymer. Additionally, the invention relates to a pharmaceutical kit comprising the compositions of the present invention.
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